Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Paris (100% of total searches to La Défense). The next most popular destinations are Levallois-Perret (0%) and Colombes (0%). Searches for hotels in Nanterre (0%) are also popular.
KAYAK users have found double rooms in La Défense for as cheap as $40 (Paris) in the last 3 days. The average price is $458.